There are also quite a few D/ST sleepers and streaming options based on matchups and injury absences, so let’s take a look at the full fantasy football defense rankings for Week 5. 

MORE: Week 5 fantasy football rankings:Quarterbacks | Running backs | Wide receivers | Tight ends | Kickers

Week 5 fantasy football rankings, Defenses

  1. Broncos at Raiders. The Raiders offense has improved, but the Broncos are fantasy’s leading D/ST through four weeks. 

  2. Cardinals at Lions. We’ll go against Matthew Stafford any chance we get. 

  3. Seahawks at Bengals. Tough road matchup, but always trust the Seahawks. 

  4. Eagles vs. Saints. Drew Brees is no longer feared with a weak shoulder and even weaker pass-catchers. Fire up the Eagles D/ST at home. 

  5. Bills at Titans. The Bills D has been underwhelming, but the Titans are allowing 12 fantasy points per game to defenses and four sacks per game. Rookie QB Marcus Mariota could make some mistakes if the Bills can pressure him. 

  6. Chiefs vs. Bears. Even with Jay Cutler and maybe Alshon Jeffery back, this is a great matchup for the Chiefs. The Bears are allowing the second-most FPPG to defenses. 

MORE: Best fantasy football pickups for Week 5

  1. Patriots at Cowboys. You know the Patriots are going to focus on shutting down Terrance Williams and pressuring Brandon Weeden into mistakes. 

  2. Packers vs. Rams. The Rams are allowing 12.5 fantasy points per game to D/STs, though the emergence of Todd Gurley is a bit of a concern. 

  3. Ravens vs. Browns. The Browns are allowing 3.5 sacks per game and putting the ball on the ground twice per contest. Expect the Ravens to take advantage. 

  4. Bengals vs. Seahawks. The Seahawks are actually allowing four sacks per game, which plays to the strength of Cincinnati’s talented defense, which has 11 QB takedowns and seven takeaways. 

  5. Texans vs. Colts. The Texans’ D is struggling horribly, BUT this home matchup in primetime looks pretty good whether Andrew Luck (shoulder) plays or not. 

  6. Giants vs. 49ers. No team allows more FPPG to defenses than the 49ers, thanks to Colin Kaepernick’s (and the entire 49ers offense’s) continued struggles. 

  7. Falcons vs. Redskins. The Falcons D/ST could continue making big plays against a turnover-prone Redskins team. 

  8. Lions vs. Cardinals. Carson Palmer looked mortal (and immobile) last week against St. Louis and could be in for another rough day against Detroit’s pass rush. We worry about a high-scoring game, though. 

  9. Steelers at Chargers. The Chargers are allowing a dozen FPPG to defenses. 

  10. Jaguars at Bucs. Deep sleeper vs. Jameis Winston, who already has eight turnovers. 

Best of the rest

  1. Colts at Texans 18. Browns at Ravens 19. Rams at Packers 20. Cowboys vs. Patriots 21. Chargers vs. Steelers 22. Redskins at Falcons 23. Saints at Eagles  24. Buccaneers vs. Jaguars 25. Bears at Chiefs 26. Titans vs. BIlls 27. Raiders vs. Broncos 28. 49ers at Giants

BYES: Dolphins, Jets, Panthers, Vikings

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